Flutonidine
Based on 1 Customer Validation
Flutonidine (ST-600) is a Clonidine (HY-12721) analogue that shows antihypertensive and sympatholytic effects. The initial hypertension produced by Flutonidine is due to stimulation of the peripheral α1, α2 adrenoceptors and the subsequent fall in blood pressure is due to the stimulation of central α2 adrenoceptors. Flutonidine reduces the arrhythmogenic and lethal effects of ouabain. Flutonidine is promising for research of ventricular arrhythmias caused by cardiac glycosides.
For research use only. We do not sell to patients.
- Purity: 98.02%
- CAS No.: 28125-87-3
- Formula: C10H12FN3
- Molecular Weight:193.22
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Adrenergic Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 28125-87-3
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Appearance Solid
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Molecular Weight 193.22
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Formula C10H12FN3
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Color Off-white to light brown
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SMILES
FC1=CC=C(C)C(NC2=NCCN2)=C1
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Synonyms
ST-600
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (258.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1754 mL | 25.8772 mL | 51.7545 mL | 129.3862 mL |
| 5 mM | 1.0351 mL | 5.1754 mL | 10.3509 mL | 25.8772 mL | |
| 10 mM | 0.5175 mL | 2.5877 mL | 5.1754 mL | 12.9386 mL | |
| 15 mM | 0.3450 mL | 1.7251 mL | 3.4503 mL | 8.6257 mL | |
| 20 mM | 0.2588 mL | 1.2939 mL | 2.5877 mL | 6.4693 mL | |
| 25 mM | 0.2070 mL | 1.0351 mL | 2.0702 mL | 5.1754 mL | |
| 30 mM | 0.1725 mL | 0.8626 mL | 1.7251 mL | 4.3129 mL | |
| 40 mM | 0.1294 mL | 0.6469 mL | 1.2939 mL | 3.2347 mL | |
| 50 mM | 0.1035 mL | 0.5175 mL | 1.0351 mL | 2.5877 mL | |
| 60 mM | 0.0863 mL | 0.4313 mL | 0.8626 mL | 2.1564 mL | |
| 80 mM | 0.0647 mL | 0.3235 mL | 0.6469 mL | 1.6173 mL | |
| 100 mM | 0.0518 mL | 0.2588 mL | 0.5175 mL | 1.2939 mL |