Aucuparin
Aucuparin, a natural product found in Sorbus aucuparia, inhibits pulmonary fibrosis in a bleomycin (HY-108345)-induced lung fibrosis mouse model. Aucuparin has anti-inflammatory activity and can inhibit the activation of inflammatory factors by TGF-β.
For research use only. We do not sell to patients.
- CAS No.: 3687-28-3
- Formula: C14H14O3
- Molecular Weight:230.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>10 μM
Compound: 8
|
Cytotoxicity against human A549 cells by SRB assay
Cytotoxicity against human A549 cells by SRB assay
|
[PMID: 19813743] |
| BV-2 | IC50 |
50.15 μM
Compound: 3
|
Anti-neuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess assay
Anti-neuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess assay
|
[PMID: 26706168] |
| HCT-15 | IC50 |
>10 μM
Compound: 8
|
Cytotoxicity against human HCT15 cells by SRB assay
Cytotoxicity against human HCT15 cells by SRB assay
|
[PMID: 19813743] |
| SK-MEL-2 | IC50 |
>10 μM
Compound: 8
|
Cytotoxicity against human SK-MEL-2 cells by SRB assay
Cytotoxicity against human SK-MEL-2 cells by SRB assay
|
[PMID: 19813743] |
| SK-OV-3 | IC50 |
>10 μM
Compound: 8
|
Cytotoxicity against human SKOV3 cells by SRB assay
Cytotoxicity against human SKOV3 cells by SRB assay
|
[PMID: 19813743] |
Chemical Information
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CAS No. 3687-28-3
-
Molecular Weight 230.26
-
Formula C14H14O3
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SMILES
OC1=C(OC)C=C(C=C1OC)C2=CC=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)