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Cat. No.: HY-101971R

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AZ PFKFB3 26 (Standard)

AZ PFKFB3 26 (Standard) is the analytical standard of AZ PFKFB3 26 (HY-101971). This product is intended for research and analytical applications. AZ PFKFB3 26 is a potent and selective PFKFB3 inhibitor with an IC₅₀ of 23 nM. AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC₅₀s of 2.06 and 0.384 μM, respectively. AZ PFKFB3 26 can be used in the study of non-small cell lung cancer.

For research use only. We do not sell to patients.

CAS No.: 1704740-52-2
Formula: C₂₄H₂₆N₄O₂
Molecular Weight:402.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

AZ PFKFB3 26 (Standard) Chemical Structure

CAS No.: 1704740-52-2

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Fluorescent Dye

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1704740-52-2
Molecular Weight 402.49
Formula C₂₄H₂₆N₄O₂
SMILES

O=C([C@H]1NCCC1)NC2=CC=C(OC3=CC4=C(N(CC(C)C)C=C4C#N)C=C3)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Boyd S, et al. Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3. J Med Chem. 2015 Apr 23;58(8):3611-25. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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