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Cat. No.: HY-W020788R

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Benoxacor (Standard)

(Synonyms: CGA 154281 (Standard))

Benoxacor (Standard) is the analytical standard of Benoxacor. This product is intended for research and analytical applications. Benoxacor (CGA 154281) is a herbicide safener and xenobiotic metabolism regulator. Benoxacor protects maize from the toxicity of metolachlor mainly by inducing detoxifying enzymes such as Glutathione S-transferase. Benoxacor also activates FXR, PXR and ERRα, and inhibits aromatase (aromatase). However, Benoxacor exhibits potential subacute oral toxicity and a high risk of hepatotoxicity in animal models. Benoxacor induces reactive oxygen species accumulation, interferes with embryonic heart development, and causes increased liver and kidney weights as well as alterations in gut microbiota in mice. Benoxacor can be used in studies related to hepatic steatosis, infertility, breast cancer and developmental toxicity.

For research use only. We do not sell to patients.

CAS No.: 98730-04-2
Formula: C₁₁H₁₁Cl₂NO₂
Molecular Weight:260.12

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Benoxacor (Standard) Chemical Structure

CAS No.: 98730-04-2

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Product Information
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Chemical Information
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Bioz

Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 98730-04-2
Molecular Weight 260.12
Formula C₁₁H₁₁Cl₂NO₂
SMILES

ClC(Cl)C(N1C(C)COC2=CC=CC=C21)=O
Synonyms

CGA 154281 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Simonsen D, et al. The Effects of Benoxacor on the Liver and Gut Microbiome of C57BL/6 Mice. Toxicol Sci. 2022;186(1):102-117. [Content Brief]

[2]. Zhang W, et al. Benoxacor caused developmental and cardiac toxicity in zebrafish larvae. Ecotoxicol Environ Saf. 2021;224:112696. [Content Brief]

[3]. Miller K D, Irzyk G P, FuERsT E P. Benoxacor treatment increases glutathione S-transferase activity in suspension cultures of Zea mays[J]. Pesticide biochemistry and physiology, 1994, 48(2): 123-134.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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