BHF177
BHF177 is a positive modulator of GABAB receptors that can block the interaction between nicotine and the brain's dopamine system, thereby reducing the addictive properties of nicotine. BHF177 is expected to be used in research related to smoking cessation.
For research use only. We do not sell to patients.
- CAS No.: 917896-43-6
- Formula: C19H20F3N3
- Molecular Weight:347.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NIH3T3 | IC50 |
35 μM
Compound: BHF177
|
Cytotoxicity against mouse NIH/3T3 cells after 24 hrs by neutral red staining-based UV/visible spectrophotometric analysis
Cytotoxicity against mouse NIH/3T3 cells after 24 hrs by neutral red staining-based UV/visible spectrophotometric analysis
|
[PMID: 23544432] |
Chemical Information
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CAS No. 917896-43-6
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Molecular Weight 347.38
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Formula C19H20F3N3
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SMILES
FC(C1=CC=C(C2=CN=C(C)N=C2N[C@H]3[C@](C4)([H])CC[C@]4([H])C3)C=C1)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)