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BIIE-0246 dihydrochloride

(Synonyms: AR-H 053591 dihydrochloride)
2 Cited Publications
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Based on 2 publication(s) in Google Scholar

BIIE-0246 dihydrochloride (AR-H 053591 dihydrochloride) is a potent and highly selective non-peptide neuropeptide Y (NPY) Y2 receptor antagonist, with an IC50 value of 15 nM.

For research use only. We do not sell to patients.

  • CAS No.: 246146-31-6
  • Formula: C49H59Cl2N11O6
  • Molecular Weight:968.97
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • BIIE-0246 dihydrochloride Chemical Structure
    BIIE-0246 dihydrochloride Chemical Structure
  • Experimental Validation Results for BIIE-0246 dihydrochloride
CAS No.: 246146-31-6
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Publications Citing Use of MedChemExpress (MCE) BIIE-0246 dihydrochloride

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In Vivo Efficacy Study
  • In Vivo Efficacy Study

All Neuropeptide Y Receptor Isoforms

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  • BIIE-0246 dihydrochloride Chemical Structure
    BIIE-0246 dihydrochloride Chemical Structure
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    BIIE-0246 dihydrochloride purchased from MedChemExpress. Usage Cited in: In Vivo. 2024 May-Jun;38(3):1133-1142. [Abstract]

    Customer Validation
     BIIE-0246 (3 μg; i.c.v.; 10 μL) reversed the antinociceptive effect of NPY. PWT was measured using von Frey filaments and PWL was measured using a hot plate experiment Sprague-Dawley rat with Cancer-induced bone pain (CIBP).

  • BIIE-0246 dihydrochloride