Acanthamoebiasis

Definition:

Acanthamoebiasis is a rare infectious disease caused by free-living amoebae belonging to the genus Acanthamoeba. Acanthamoeba are the causative agents of granulomatous amebic encephalitis (GAE) and amebic keratitis (AK). They also have been associated with cutaneous lesions and sinusitis in individuals with compromised immune systems. Acanthamoeba are widely distributed in the environment, including soil, water and air. Entry can occur through the eye, the nasal passages, or ulcerated or broken skin.

References:

[1]. Francine Marciano-Cabral, et al. Acanthamoeba spp. as agents of disease in humans. Clin Microbiol Rev. 2003 Apr;16(2):273-307. [Content Brief]

[2]. Karolina Kot, et al. Amoebas from the genus Acanthamoeba and their pathogenic properties. Ann Parasitol. 2018;64(4):299-308. [Content Brief]

[3]. Sonali K Kalra, et al. Acanthamoeba and its pathogenic role in granulomatous amebic encephalitis. Exp Parasitol. 2020 Jan;208:107788. [Content Brief]

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