1. GPCR/G Protein
  2. Neuropeptide Y Receptor
  3. BMS-193885

BMS-193885 

Cat. No.: HY-120619
Handling Instructions

BMS-193885 is a potent, selective, competitive, and brain penetrant neuropeptide Y1 receptor antagonist with a Ki of 3.3 nM, and has an IC50 of 5.9 nM for hY1, which displays > 100, > 160, > 160 and > 160-fold selectivity over α1, hY2, hY4 and hY5 receptors, respectively .

For research use only. We do not sell to patients.

BMS-193885 Chemical Structure

BMS-193885 Chemical Structure

CAS No. : 186185-03-5

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Description

BMS-193885 is a potent, selective, competitive, and brain penetrant neuropeptide Y1 receptor antagonist with a Ki of 3.3 nM, and has an IC50 of 5.9 nM for hY1, which displays > 100, > 160, > 160 and > 160-fold selectivity over α1, hY2, hY4 and hY5 receptors, respectively [1] [2].

IC50 & Target

Ki: 3.3 nM (Neuropeptide Y1 receptor)[1]
IC50: 5.9 nM (hY1)[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

590.71

Formula

C₃₃H₄₂N₄O₆

CAS No.

186185-03-5

SMILES

O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC(NC(NCCCN3CCC(C4=CC=CC(OC)=C4)CC3)=O)=C2)OC

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
BMS-193885
Cat. No.:
HY-120619
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BMS-193885

Cat. No.: HY-120619