BMS-986144 (non-deuterated)
BMS-986144 non-deuterated is the non-tritium form of BMS-986144 (HY-131905S). BMS-986144 non-deuterated is an orally active inhibitor of HCV NS3/4A protease. BMS-986144 non-deuterated binds to the active site of HCV NS3/4A protease and induces conformational changes in the protease. BMS-986144 non-deuterated reduces time-dependent CYP3A4 inhibition, exhibits hepatic microsomal metabolic stability, and undergoes oxidation of the macrocyclic linker chain. BMS-986144 non-deuterated can be used in studies related to hepatitis C virus infection.
For research use only. We do not sell to patients.
- CAS No.: 1410114-25-8
- Formula: C40H51F4N5O9S
- Molecular Weight:853.92
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1410114-25-8
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Molecular Weight 853.92
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Formula C40H51F4N5O9S
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SMILES
O=C(OC(C)(C)C(F)(F)F)N[C@H]1[C@H](CC)C[C@H](C)CC/C=C\[C@@]2([H])[C@](C2)(C(NS(=O)(C3(C)CC3)=O)=O)NC([C@@](C[C@@H](OC4=NC=CC5=C4C=C(F)C(OC)=C5)C6)([H])N6C1=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)