BODIPY TR Cadaverine

Name: BODIPY TR Cadaverine
Brand: MedChemExpress
SKU: HY-D1594
Rating: 4.5 (1 reviews)

Cat. No.: HY-D1594 Purity: 96.10%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

BODIPY TR Cadaverine, a cadaverine derivative, is a red fluorescent dye. BODIPY TR Cadaverine can be used in a a highly sensitive and robust fluorescent displacement assay, which binds to native LPS strongly, specifically recognizing lipid A, and is competitively displaced by compounds displaying an affinity for lipid A.

For research use only. We do not sell to patients.

BODIPY TR Cadaverine Chemical Structure

CAS No. : 217190-24-4

Size	Price	Stock	Quantity
1 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 330	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 560	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

In Vitro

BODIPY TR Cadaverine assay^[1] (to quantify autophagy in cells):
Cells were incubated with 125 nM BODIPY TR Cadaverine for 10 minutes, washed four times with PBS and lysed in 10 mM Tris-Cl pH 8, 0.1 % Triton X-100. Fluorescence levels were read in a SPECTRAmax fluorimeter (Molecular Devices) (λex=588 nm, λem=616 nm). Fluorescence levels were normalized for cell number by adding 0.2 mM ethidium bromide and reading DNA fluorescence (λex=530 nm, λem=590 nm)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

544.85

Formula

C₂₆H₂₈BClF₂N₄O₂S

CAS No.

217190-24-4

Appearance

Solid

Color

Dark purple to black

Emission (Em)

615

Excitation (Ex)

589

SMILES

[F-][B+3]1([N-]2C(C=C(C=C3)[N]1=C3C4=CC=C(OCC(NCCCCCN)=O)C=C4)=CC=C2C5=CC=CS5)[F-].Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (229.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.8354 mL	9.1768 mL	18.3537 mL
5 mM	0.3671 mL	1.8354 mL	3.6707 mL
10 mM	0.1835 mL	0.9177 mL	1.8354 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 96.10%

Select Batch:

Data Sheet (273 KB) SDS (252 KB)

COA (252 KB) HNMR (300 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. Carreira RS, et al. Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells. Autophagy. 2010 May;6(4):462-72. [Content Brief]

[2]. Wood SJ, et al. Anti-endotoxin agents. 1. Development of a fluorescent probe displacement method optimized for the rapid identification of lipopolysaccharide-binding agents. Comb Chem High Throughput Screen. 2004 May;7(3):239-49. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.8354 mL	9.1768 mL	18.3537 mL	45.8842 mL
	5 mM	0.3671 mL	1.8354 mL	3.6707 mL	9.1768 mL
	10 mM	0.1835 mL	0.9177 mL	1.8354 mL	4.5884 mL
	15 mM	0.1224 mL	0.6118 mL	1.2236 mL	3.0589 mL
	20 mM	0.0918 mL	0.4588 mL	0.9177 mL	2.2942 mL
	25 mM	0.0734 mL	0.3671 mL	0.7341 mL	1.8354 mL
	30 mM	0.0612 mL	0.3059 mL	0.6118 mL	1.5295 mL
	40 mM	0.0459 mL	0.2294 mL	0.4588 mL	1.1471 mL
	50 mM	0.0367 mL	0.1835 mL	0.3671 mL	0.9177 mL
	60 mM	0.0306 mL	0.1529 mL	0.3059 mL	0.7647 mL
	80 mM	0.0229 mL	0.1147 mL	0.2294 mL	0.5736 mL
	100 mM	0.0184 mL	0.0918 mL	0.1835 mL	0.4588 mL