BODIPY TR Cadaverine
Based on 7 publication(s) in Google Scholar
BODIPY TR Cadaverine, a cadaverine derivative, is a red fluorescent dye. BODIPY TR Cadaverine can be used in a a highly sensitive and robust fluorescent displacement assay, which binds to native LPS strongly, specifically recognizing lipid A, and is competitively displaced by compounds displaying an affinity for lipid A.
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- Pureté : 99.08%
- CAS No.: 217190-24-4
- Formule: C26H28BClF2N4O2S
- Masse moléculaire:544.85
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Stockage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) BODIPY TR Cadaverine
More- Adv Funct Mater. 2026 Jun 12.
- Adv Sci (Weinh). 2025 Apr;12(14):e2411923. [Abstract]
- Acta Biomater. 2026 Aug 21:S1742-7061(26)00574-X.
- Virulence. 2026 Dec 31;17(1):2707759.
- Antibiotics (Basel). 2024 Jun 13;13(6):555. [Abstract]
- PLoS Pathog. 2025 Dec 29;21(12):e1013843. [Abstract]
- ACS Infect Dis. 2026 Jul 10;12(7):2288-2302. [Abstract]
Customer Validation & Images
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Bio/Physico-chemical Assay
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Bio/Physico-chemical Assay
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Bio/Physico-chemical Assay
Activité biologique
Description
In Vitro
Guide (The following is our recommended protocol. This protocol is only a guide and should be modified according to your specific needs).
BODIPY TR Cadaverine assay[1] (to quantify autophagy in cells):
Cells were incubated with 125 nM BODIPY TR Cadaverine for 10 minutes, washed four times with PBS and lysed in 10 mM Tris-Cl pH 8, 0.1 % Triton X-100. Fluorescence levels were read in a SPECTRAmax fluorimeter (Molecular Devices) (λex=588 nm, λem=616 nm). Fluorescence levels were normalized for cell number by adding 0.2 mM ethidium bromide and reading DNA fluorescence (λex=530 nm, λem=590 nm)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Emission (Em)
615
Excitation (Ex)
589
Chemical Information
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CAS No. 217190-24-4
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Appearance Solid
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Masse moléculaire 544.85
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Formule C26H28BClF2N4O2S
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Color Dark purple to black
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SMILES
[F-][B+3]1([N-]2C(C=C(C=C3)[N]1=C3C4=CC=C(OCC(NCCCCCN)=O)C=C4)=CC=C2C5=CC=CS5)[F-].Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (7)
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Journal Impact Factor
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Most Recent
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BODIPY TR Cadaverine purchased from MedChemExpress. Usage Cited in: Adv Funct Mater. 2026 Jun 12.
The responsiveness of free RWY, MCPR-released RWY, and Cu2+-treated RWY to LPS or LTA was compared using BODIPY TR Cadaverine fluorescence detection (5.0 μg/mL; 4 h labeling of LPS/LTA, followed by a further 1 h incubation of the diluted labeled material with the samples).
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Adv Sci (Weinh)
2025 Apr;12(14):e2411923. PMID: 39888292
BODIPY TR Cadaverine purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Apr;12(14):e2411923. [Abstract]
Competitive binding assay between A20 and the fluorescent probe BODIPY-TR-cadaverine (5 μM; pre-incubated with lipid A for 15 min followed by an 80 min measurement after addition of the tested compounds) in the presence of lipid A. BODIPY-TR-cadaverine bound to free lipid A, resulting in fluorescence quenching.
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Antibiotics (Basel)
Mechanistic Study of Antimicrobial Effectiveness of Cyclic Amphipathic Peptide [R4W4] against Methicillin-Resistant Staphylococcus aureus Clinical Isolates. [Abstract]2024 Jun 13;13(6):555. PMID: 38927221
BODIPY TR Cadaverine purchased from MedChemExpress. Usage Cited in: Antibiotics (Basel). 2024 Jun 13;13(6):555. [Abstract]
LTA binding affinity of [R4W4], melittin, and vancomycin using BODIPY-TR-cadaverine (5 μg/mL; 4 h incubation with Staphylococcus aureus LTA followed by a further 1 h incubation after addition of the tested antibacterial agents) fluorescent dye.
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PLoS Pathog
A lignan compound regulates LPS modifications via PmrA/B signaling cascades to potentiate colistin efficacy in vivo. [Abstract]2025 Dec 29;21(12):e1013843. PMID: 41460948 -
ACS Infect Dis
Indolicidin Attenuates Inflammation by Modulating the TLR4 Signaling Pathway during Sepsis Progression. [Abstract]2026 Jul 10;12(7):2288-2302. PMID: 42305095
Solvant et solubilité
In Vitro:
DMSO : 125 mg/mL (229.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Carreira RS, et al. Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells. Autophagy. 2010 May;6(4):462-72. [Content Brief]
[2]. Wood SJ, et al. Anti-endotoxin agents. 1. Development of a fluorescent probe displacement method optimized for the rapid identification of lipopolysaccharide-binding agents. Comb Chem High Throughput Screen. 2004 May;7(3):239-49. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8354 mL | 9.1768 mL | 18.3537 mL | 45.8842 mL |
| 5 mM | 0.3671 mL | 1.8354 mL | 3.6707 mL | 9.1768 mL | |
| 10 mM | 0.1835 mL | 0.9177 mL | 1.8354 mL | 4.5884 mL | |
| 15 mM | 0.1224 mL | 0.6118 mL | 1.2236 mL | 3.0589 mL | |
| 20 mM | 0.0918 mL | 0.4588 mL | 0.9177 mL | 2.2942 mL | |
| 25 mM | 0.0734 mL | 0.3671 mL | 0.7341 mL | 1.8354 mL | |
| 30 mM | 0.0612 mL | 0.3059 mL | 0.6118 mL | 1.5295 mL | |
| 40 mM | 0.0459 mL | 0.2294 mL | 0.4588 mL | 1.1471 mL | |
| 50 mM | 0.0367 mL | 0.1835 mL | 0.3671 mL | 0.9177 mL | |
| 60 mM | 0.0306 mL | 0.1529 mL | 0.3059 mL | 0.7647 mL | |
| 80 mM | 0.0229 mL | 0.1147 mL | 0.2294 mL | 0.5736 mL | |
| 100 mM | 0.0184 mL | 0.0918 mL | 0.1835 mL | 0.4588 mL |
BODIPY TR Cadaverine Related Classifications
HY-D1594 Related Classifications
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