BODIPY TR Cadaverine
Based on 5 publication(s) in Google Scholar
BODIPY TR Cadaverine, a cadaverine derivative, is a red fluorescent dye. BODIPY TR Cadaverine can be used in a a highly sensitive and robust fluorescent displacement assay, which binds to native LPS strongly, specifically recognizing lipid A, and is competitively displaced by compounds displaying an affinity for lipid A.
For research use only. We do not sell to patients.
- Purity: 99.05%
- CAS No.: 217190-24-4
- Formula: C26H28BClF2N4O2S
- Molecular Weight:544.85
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) BODIPY TR Cadaverine
More
Biological Activity
Guide (The following is our recommended protocol. This protocol is only a guide and should be modified according to your specific needs).
BODIPY TR Cadaverine assay[1] (to quantify autophagy in cells):
Cells were incubated with 125 nM BODIPY TR Cadaverine for 10 minutes, washed four times with PBS and lysed in 10 mM Tris-Cl pH 8, 0.1 % Triton X-100. Fluorescence levels were read in a SPECTRAmax fluorimeter (Molecular Devices) (λex=588 nm, λem=616 nm). Fluorescence levels were normalized for cell number by adding 0.2 mM ethidium bromide and reading DNA fluorescence (λex=530 nm, λem=590 nm)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Chemical Information
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CAS No. 217190-24-4
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Appearance Solid
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Molecular Weight 544.85
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Formula C26H28BClF2N4O2S
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Color Dark purple to black
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SMILES
[F-][B+3]1([N-]2C(C=C(C=C3)[N]1=C3C4=CC=C(OCC(NCCCCCN)=O)C=C4)=CC=C2C5=CC=CS5)[F-].Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (5)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
2025 Apr;12(14):e2411923. PMID: 39888292 -
Antibiotics (Basel)
Mechanistic Study of Antimicrobial Effectiveness of Cyclic Amphipathic Peptide [R4W4] against Methicillin-Resistant Staphylococcus aureus Clinical Isolates. [Abstract]2024 Jun 13;13(6):555. PMID: 38927221 -
PLoS Pathog
A lignan compound regulates LPS modifications via PmrA/B signaling cascades to potentiate colistin efficacy in vivo. [Abstract]2025 Dec 29;21(12):e1013843. PMID: 41460948 -
ACS Infect Dis
Indolicidin Attenuates Inflammation by Modulating the TLR4 Signaling Pathway during Sepsis Progression. [Abstract]2026 Jul 10;12(7):2288-2302. PMID: 42305095
Solvent & Solubility
DMSO : 125 mg/mL (229.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
[1]. Carreira RS, et al. Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells. Autophagy. 2010 May;6(4):462-72. [Content Brief]
[2]. Wood SJ, et al. Anti-endotoxin agents. 1. Development of a fluorescent probe displacement method optimized for the rapid identification of lipopolysaccharide-binding agents. Comb Chem High Throughput Screen. 2004 May;7(3):239-49. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8354 mL | 9.1768 mL | 18.3537 mL | 45.8842 mL |
| 5 mM | 0.3671 mL | 1.8354 mL | 3.6707 mL | 9.1768 mL | |
| 10 mM | 0.1835 mL | 0.9177 mL | 1.8354 mL | 4.5884 mL | |
| 15 mM | 0.1224 mL | 0.6118 mL | 1.2236 mL | 3.0589 mL | |
| 20 mM | 0.0918 mL | 0.4588 mL | 0.9177 mL | 2.2942 mL | |
| 25 mM | 0.0734 mL | 0.3671 mL | 0.7341 mL | 1.8354 mL | |
| 30 mM | 0.0612 mL | 0.3059 mL | 0.6118 mL | 1.5295 mL | |
| 40 mM | 0.0459 mL | 0.2294 mL | 0.4588 mL | 1.1471 mL | |
| 50 mM | 0.0367 mL | 0.1835 mL | 0.3671 mL | 0.9177 mL | |
| 60 mM | 0.0306 mL | 0.1529 mL | 0.3059 mL | 0.7647 mL | |
| 80 mM | 0.0229 mL | 0.1147 mL | 0.2294 mL | 0.5736 mL | |
| 100 mM | 0.0184 mL | 0.0918 mL | 0.1835 mL | 0.4588 mL |
BODIPY TR Cadaverine Related Classifications
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