1. Protein Tyrosine Kinase/RTK
  2. c-Fms
  3. c-Fms-IN-1

c-Fms-IN-1 

Cat. No.: HY-18791 Purity: 99.85%
Handling Instructions

c-Fms-IN-1 is a FMS kinase inhibitor with an IC50 of 0.0008 μM.

For research use only. We do not sell to patients.

c-Fms-IN-1 Chemical Structure

c-Fms-IN-1 Chemical Structure

CAS No. : 885703-64-0

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 165 In-stock
Estimated Time of Arrival: December 31
5 mg USD 150 In-stock
Estimated Time of Arrival: December 31
10 mg USD 250 In-stock
Estimated Time of Arrival: December 31
50 mg USD 750 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1200 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

c-Fms-IN-1 is a FMS kinase inhibitor with an IC50 of 0.0008 μM[1].

IC50 & Target

FMS kinase[1]

Molecular Weight

393.48

Formula

C₂₂H₂₇N₅O₂

CAS No.

885703-64-0

SMILES

CN1CCN(C2=CC=C(NC(C3=CC=C(C#N)O3)=O)C(N4CCCCC4)=C2)CC1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (12.71 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5414 mL 12.7071 mL 25.4143 mL
5 mM 0.5083 mL 2.5414 mL 5.0829 mL
10 mM 0.2541 mL 1.2707 mL 2.5414 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 0.5 mg/mL (1.27 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 0.5 mg/mL (1.27 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.85%

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
c-Fms-IN-1
Cat. No.:
HY-18791
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