YM-49598 iodide
YM-49598 iodide is a tachykinin NK-1 receptor antagonist. YM-49598 iodide can inhibit drug-induced bladder contraction in rats, with IC50 of 11 μg/kg.
For research use only. We do not sell to patients.
- CAS No.: 476494-44-7
- Formula: C36H45Cl2IN2O2
- Molecular Weight:735.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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NK1R |
Chemical Information
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CAS No. 476494-44-7
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Molecular Weight 735.57
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Formula C36H45Cl2IN2O2
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SMILES
CC(C)OC1=CC(CC(N2CC(C3=CC=C(C(Cl)=C3)Cl)(CCC2)CC[N+]4(CCC(CC4)C5=CC=CC=C5)C)=O)=CC=C1.[I-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)