ZW290
Based on 1 Customer Validation
ZW290 is a compound to activate brown adipose tissue (BAT) thermogenic function. ZW290 increases the expression of uncoupling Protein 1 (UCP1) protein and inhibits ATP synthesis in BAT.
For research use only. We do not sell to patients.
- Purity: 99.60%
- CAS No.: 2411852-67-8
- Formula: C20H18N2O6S
- Molecular Weight:414.43
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
ZW290 in brown adipose tissue (BAT) induces nonshivering thermogenesis by limiting the oxidation of lipid droplet-derived fatty acids and increasing UCP1 protein levels[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Kunming (KM) mice (20 g) keeping under acute cold exposure (-20°C)[1]
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Dosage:25 mg/kg, 50 mg/kg, or 100 mg/kg
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Administration:Oral gavage; once a day; for 7 days
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Result:Notably decreased the size of lipid droplets in BAT and increased the content of mitochondria and the expression of UCP1 in BAT and WAT.
Chemical Information
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CAS No. 2411852-67-8
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Appearance Solid
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Molecular Weight 414.43
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Formula C20H18N2O6S
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Color Yellow to brown
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SMILES
O=C1N(C2=CC=C(C=C2)OC)C(N/C1=C\C3=CC(OC)=C(C=C3)OCC(O)=O)=S
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)