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Brezosiran

Brezosiran is a siRNA that inhibits huntingtin synthesis.

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  • Brezosiran Chemical Structure
    Brezosiran Chemical Structure
CAS No.: 3059403-91-4
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  • Brezosiran Chemical Structure
    Brezosiran Chemical Structure RNA, ((5′,6′-dideoxy-6′-phosphono-β-D-ribo-hex-5-enofurano)Um-sp-(2′-deoxy-2′-fluoro)A-sp-Um-Cm-dA-Gm-C-(2′→5′)-Um-Um-Um-Um-dC-Cm-(2′-deoxy-2′-fluoro)A-Gm-dG-Gm-Um-Cm-Gm-Cm-sp-Cm-sp-Gm), complex with RNA (Gm-sp-Cm-sp-Gm-Am-Cm-(2′-O-hexadecyl)C-(2′-deoxy-2′-fluoro)C-Um-(2′-deoxy-2′-fluoro)G-(2′-deoxy-2′-fluoro)G-(2′-deoxy-2′-fluoro)A-Am-Am-Am-Gm-Cm-Um-Gm-Am-sp-Um-sp-Am) (1:1)
    1/16
  • RNA, ((5′,6′-dideoxy-6′-phosphono-β-D-ribo-hex-5-enofurano)Um-sp-(2′-deoxy-2′-fluoro)A-sp-Um-Cm-dA-Gm-C-(2′→5′)-Um-Um-Um-Um-dC-Cm-(2′-deoxy-2′-fluoro)A-Gm-dG-Gm-Um-Cm-Gm-Cm-sp-Cm-sp-Gm), complex with RNA (Gm-sp-Cm-sp-Gm-Am-Cm-(2′-O-hexadecyl)C-(2′-deoxy-2′-fluoro)C-Um-(2′-deoxy-2′-fluoro)G-(2′-deoxy-2′-fluoro)G-(2′-deoxy-2′-fluoro)A-Am-Am-Am-Gm-Cm-Um-Gm-Am-sp-Um-sp-Am) (1:1)