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Cat. No.: HY-103041

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TP-061

TP-061 (Compound 30) is a Brr2 inhibitor with an IC₅₀ of 42 nM for Brr2 ATPase.

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CAS No.: 2133440-09-0
Formule: C₂₁H₂₅FN₄O₂
Masse moléculaire:384.45

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

TP-061 Chemical Structure

CAS No.: 2133440-09-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

TP-061 (Compound 30) is a Brr2 inhibitor with an IC₅₀ of 42 nM for Brr2 ATPase^[1].

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Chemical Information

CAS No. 2133440-09-0
Masse moléculaire 384.45
Formule C₂₁H₂₅FN₄O₂
SMILES

O=C1NC2=C(C=C(F)C=C2)[C@]13N(C(C4=CN(C)C=N4)=O)[C@@H](CC(C)C)C[C@H]3C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Ito M, et al. Discovery of spiro[indole-3,2'-pyrrolidin]-2(1H)-one based inhibitors targeting Brr2, a core component of the U5 snRNP. Bioorg Med Chem. 2017 Sep 1;25(17):4753-4767. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
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TP-061

Voir tous les produits spécifiques à Isoform DNA/RNA Synthesis

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

TP-061 Related Classifications

HY-103041 Related Classifications

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