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Cat. No.: HY-N3764

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Diosbulbin C

Diosbulbin C is a diterpene lactone component, which can be extracted from traditional Chinese medicine Dioscorea bulbifera L.. Diosbulbin C possesses high anticancer activity in non-small cell lung cancer (NSCLC). Diosbulbin C could induce cell cycle arrest at G0/G1 phase in NSCLC. Diosbulbin C also inhibits the proliferation of NSCLC cells, possibly by downregulating the expression/activation of AKT, DHFR, and TYMS.

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CAS No.: 20086-07-1
Formule: C₁₉H₂₂O₇
Masse moléculaire:362.37

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Diosbulbin C Chemical Structure

CAS No.: 20086-07-1

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Description

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Chemical Information

CAS No. 20086-07-1
Masse moléculaire 362.37
Formule C₁₉H₂₂O₇
SMILES

O=C([C@@H]1C[C@H](O)C[C@@]2([H])[C@@]3(C)[C@@](O[C@@H](C4=COC=C4)C3)(C5)C(O[C@]5([H])[C@@]21[H])=O)O
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Zhu Z, et al. Diosbulbin C, a novel active ingredient in Dioscorea bulbifera L. extract, inhibits lung cancer cell proliferation by inducing G0/G1 phase cell cycle arrest. BMC Complement Med Ther. 2023 Dec 4;23(1):436. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Diosbulbin C

Voir tous les produits spécifiques à Isoform Akt

Voir tous les produits spécifiques à Isoform Endogenous Metabolite

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Diosbulbin C Related Classifications

HY-N3764 Related Classifications