TSACC - TSSK6 activating cochaperone Gene

Also Known as SIP; SSTK-IP; C1orf182

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 128229

About TSACC

Cytogenetic location: 1q22 Genomic coordinates (GRCh38): 1:156,337,314-156,346,995 (from NCBI)

This gene has 8 transcripts (splice variants) and 87 orthologues. Restricted expression toward testis (RPKM 148.3).

Summary

Enables chaperone binding activity. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TSACC Products (11)

mRNA Protein Name
NM_001304817.2 NP_001291746.1 TSSK6-activating co-chaperone protein isoform a
NM_001304818.2 NP_001291747.1 TSSK6-activating co-chaperone protein isoform a
NM_001304819.2 NP_001291748.1 TSSK6-activating co-chaperone protein isoform a
NM_001304820.1 NP_001291749.1 TSSK6-activating co-chaperone protein isoform a
NM_001304821.2 NP_001291750.1 TSSK6-activating co-chaperone protein isoform a
NM_001304822.2 NP_001291751.1 TSSK6-activating co-chaperone protein isoform b
NM_001304823.2 NP_001291752.1 TSSK6-activating co-chaperone protein isoform b
NM_001304824.2 NP_001291753.1 TSSK6-activating co-chaperone protein isoform b
NM_001304825.2 NP_001291754.1 TSSK6-activating co-chaperone protein isoform b
NM_001304826.2 NP_001291755.1 TSSK6-activating co-chaperone protein isoform c
NM_144627.5 NP_653228.1 TSSK6-activating co-chaperone protein isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables protein-folding chaperone binding IPI
IPI: Inferred from physical interaction
20829357 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

TSSK6-activating co-chaperone protein

  • SSTK-interacting protein (SSTK-IP)

TSACC Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
TSACC Q96A04 LIX1 Homo sapiens Q8N485
Y2H Prey Pooling
32296183
Intra
TSACC Q96A04 LIX1 Homo sapiens Q8N485
Y2H Array
32296183
Intra
TSACC Q96A04 ATN1 Homo sapiens Q86V38
Validated Y2H
32814053
Intra
TSACC Q96A04 ATN1 Homo sapiens Q86V38
Y2H Array
32814053
Intra
TSACC Q96A04 ATN1 Homo sapiens Q86V38
Y2H Pooling
32814053
Intra
TSACC Q96A04 PAK1 Homo sapiens Q13153
Validated Y2H
32814053
Intra
TSACC Q96A04 PAK1 Homo sapiens Q13153
Y2H Array
32814053
Intra
TSACC Q96A04 PAK1 Homo sapiens Q13153
Y2H Pooling
32814053
Intra
TSACC Q96A04 NUP58 Homo sapiens Q9BVL2
Validated Y2H
32814053
Intra
TSACC Q96A04 NUP58 Homo sapiens Q9BVL2
Y2H Pooling
32814053
Intra
TSACC Q96A04 NUP58 Homo sapiens Q9BVL2
Y2H Array
32814053
Intra
TSACC Q96A04 FOXP2 Homo sapiens O15409
Y2H Array
32296183
Intra
TSACC Q96A04 FOXP2 Homo sapiens O15409
Y2H Prey Pooling
32296183
Intra
TSACC Q96A04 FOXP2 Homo sapiens O15409
Y2H Prey Pooling
25416956
Intra
TSACC Q96A04 FOXP2 Homo sapiens O15409
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Complete Androgen Insensitivity Syndrome

  • Cais

  • Complete Androgen Resistance Syndrome

  • Androgen Insensitivity Syndrome Complete

  • Androgen Insensitivity, Complete

  • Androgen-Insensitivity Syndrome

  • Testicular Feminization
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS15129 TSACC Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus TSACC VGNC VGNC:66604
Rattus norvegicus TSACC RGD RGD:1304953
Macaca mulatta TSACC VGNC VGNC:79861
Bos taurus TSACC VGNC VGNC:36406
Mus musculus TSACC MGD MGI:1924177
Others TSACC NCBI