SLC16A9 - solute carrier family 16 member 9 Gene

Also Known as MCT9; C10orf36

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 220963

About SLC16A9

Cytogenetic location: 10q21.2 Genomic coordinates (GRCh38): 10:59,650,764-59,710,079 (from NCBI)

This gene has 3 transcripts (splice variants), 275 orthologues and 13 paralogues. Biased expression in adrenal (RPKM 82.1), kidney (RPKM 62.2) and 9 other tissues.

Summary

Predicted to enable monocarboxylic acid transmembrane transporter activity. Involved in urate metabolic process. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC16A9 Products (6)

mRNA Protein Name
NM_001323977.1 NP_001310906.1 monocarboxylate transporter 9 isoform b
NM_001323978.2 NP_001310907.1 monocarboxylate transporter 9 isoform b
NM_001323979.2 NP_001310908.1 monocarboxylate transporter 9 isoform b
NM_001323980.2 NP_001310909.1 monocarboxylate transporter 9 isoform b
NM_001323981.2 NP_001310910.1 monocarboxylate transporter 9 isoform a
NM_194298.3 NP_919274.1 monocarboxylate transporter 9 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables carnitine transmembrane transporter activity IDA
IDA: Inferred from direct assay
21886157 GOA
enables creatine transmembrane transporter activity IDA
IDA: Inferred from direct assay
31784090 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence Références Source
involved in carnitine transmembrane transport IDA
IDA: Inferred from direct assay
21886157 GOA
involved in creatine transmembrane transport IDA
IDA: Inferred from direct assay
31784090 GOA
involved in urate metabolic process IMP
IMP: Inferred from mutant phenotype
19503597 GOA
Cellular Component GO Annotation Evidence Références Source
located in plasma membrane IDA
IDA: Inferred from direct assay
31784090 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC16A9 Protein Structure

MFS_1

MFS_1: Major Facilitator Superfamily (21 - 422)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 509 a.a.
Protein Preferred Names Protein Names

monocarboxylate transporter 9

  • MCT 9

SLC16A9 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
SLC16A9 Q7RTY1 MRPL11 Homo sapiens Q9Y3B7
Y2H Array
25416956
Intra
SLC16A9 Q7RTY1 MRPL11 Homo sapiens Q9Y3B7
Y2H Prey Pooling
25416956
Intra
SLC16A9 Q7RTY1 EIF4A2 Homo sapiens Q14240
Y2H Array
25416956
Intra
SLC16A9 Q7RTY1 KLC4 Homo sapiens Q9NSK0
Validated Y2H
25416956
Intra
SLC16A9 Q7RTY1 KLC4 Homo sapiens Q9NSK0
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Gout

  • Gouty Arthritis

  • Articular Gout

  • Gouty Arthropathy

  • Arthritis, Gouty

  • Arthritis Gouty

  • Idiopathic Gout

  • Idiopathic Gout, Unspecified Site

  • Gouty Bursitis

  • Uratic Arthritis

  • Gout Nos

  • Gouty

  • Gouty Diathesis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS13033 SLC16A9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SLC16A9 VGNC VGNC:77564
Canis familiaris SLC16A9 VGNC VGNC:46247
Bos taurus SLC16A9 VGNC VGNC:34695
Mus musculus SLC16A9 MGD MGI:1914109
Felis catus SLC16A9 VGNC VGNC:65216
Rattus norvegicus SLC16A9 RGD RGD:1596295
Others SLC16A9 NCBI