Sst - somatostatin Gene

Also Known as SRIF; Smst; SS-14; SS-28

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24797

Summary

Predicted to enable identical protein binding activity. Involved in several processes, including hyperosmotic response; response to acidic pH; and response to heat. Located in extracellular space and neuronal cell body. Biomarker of gastric ulcer; hypertension; and vascular dementia. Orthologous to human SST (somatostatin). [provided by Alliance of Genome Resources, Apr 2022]

Sst Products (1)

mRNA Protein Name
NM_012659.2 NP_036791.1 somatostatin precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Références Source
involved in hyperosmotic response IEP
IEP: Inferred from expression pattern
18992283 RGD
involved in response to acidic pH IEP
IEP: Inferred from expression pattern
18992283 RGD
involved in response to amino acid IEP
IEP: Inferred from expression pattern
17961553 RGD
involved in response to steroid hormone IEP
IEP: Inferred from expression pattern
18421448 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
18800063 RGD
Cellular Component GO Annotation Evidence Références Source
located in extracellular space IDA
IDA: Inferred from direct assay
18992283 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
18598846 RGD
is active in neuronal dense core vesicle IDA
IDA: Inferred from direct assay
2422591 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

somatostatin

  • somatotropin release-inhibiting factor

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (6)
Cat. No. Nom du produit Effect
Pureté Rare Diseases
HY-16381 Pasireotide Agonist 99.94% Yes
HY-16381A Pasireotide acetate Agonist 99.92% Unkown
HY-79135 Pasireotide ditrifluoroacetate Agonist 99.56% Yes
HY-79136 Pasireotide L-aspartate salt Agonist ≥98.0% Unkown
HY-108768 Pasireotide pamoate Agonist 99.47% Yes
HY-16381B Pasireotide (diaspartate) Agonist / Unkown

Clinical Phase

Bioactive Molecules (2)
Cat. No. Nom du produit Effect
Pureté Phase
HY-P1384 L803 Agonist / Phase 2
HY-P3294 Onzigolide Agonist / Phase 2

Pre-clinical Phase

Bioactive Molecules (40)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-P1932 Cortistatin-14 99.98% Unkown
HY-P1202 CYN 154806 Antagonist 99.96% Unkown
HY-111615A J-2156 TFA Agonist 99.88% Unkown
HY-P1932A Cortistatin-14 TFA 99.99% Unkown
HY-P1206 CH 275 Agonist 99.52% Unkown
HY-155193 XY-52 Inhibitor 99.77% Unkown
HY-P1201 Cyclosomatostatin Antagonist 99.56% Unkown
HY-111615 J-2156 Agonist 99.88% Unkown
HY-P1202A CYN 154806 TFA Antagonist 98.30% Unkown
HY-P1203 BIM-23056 Antagonist 99.98% Unkown
HY-123335A L-796778 acetate Agonist 98.00% Unkown
HY-123499 SRA880 Antagonist 98.22% Unkown
HY-108497 L-803087 Agonist 99.66% Unkown
HY-P10758 Alkyne-βAG-TOCA Agonist 98.99% Unkown
HY-P1139 Cortistatin-8 Antagonist 99.56% Unkown
HY-P2090A Angiopeptin TFA 99.01% Unkown
HY-108499 NNC 26-9100 99.3% Unkown
HY-P10741 DOTA-EB-TATE Activator 95.42% Unkown
HY-108501 (1R,1'S,3'R/1R,1'R,3'S)-L-054,264 Agonist 95.07% Unkown
HY-P3958 BIM-23027 Agonist 99.76% Unkown
HY-125382A L-797591 hydrochloride Agonist 99.81% Unkown
HY-P4469 PRL 3195 / Unkown
HY-P10239 Tyr3-Octreotate Ligand 99.76% Unkown
HY-108497A L-803087 TFA Agonist / Unkown
HY-110161 sst2 Receptor agonist-1 Agonist / Unkown
HY-123460 BN-81674 Antagonist / Unkown
HY-164399 SST0116CL1 / Unkown
HY-164399A SST0116CL1 free base Inhibitor / Unkown
HY-175053 Pasireotide (aspartate) TFA / Unkown
HY-177278 SST1 receptor antagonist-1 Antagonist / Unkown
HY-P0042 BIM-23197 Agonist / Unkown
HY-P1201A Cyclosomatostatin TFA Antagonist / Unkown
HY-P1203A BIM-23056 TFA Antagonist / Unkown
HY-P2090 Angiopeptin / Unkown
HY-RS13819 SST Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-125382 L-797591 Agonist / Unkown
HY-164040 Zavolosotine Agonist / Unkown
HY-177282 SST1 receptor antagonist-2 Antagonist / Unkown
HY-RS18024 Sst Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24497 Sst Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sst NCBI NCBI:6750