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Cat. No.: HY-117722

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JW 618

Name: JW 618
Brand: MedChemExpress
SKU: HY-117722
Price: 130.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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JW 618 is a selective ABHD6 inhibitor, with IC₅₀s of 38 and 13 nM for mouse and rat ABHD6.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Pureté: 99.9%
CAS No.: 1416133-88-4
Formule: C₁₇H₁₄F₆N₂O₂
Masse moléculaire:392.30

Stockage:

Solution, -20°C, 2 years

JW 618 Chemical Structure

CAS No.: 1416133-88-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
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- In Vitro
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Description

JW 618 is a selective ABHD6 inhibitor, with IC₅₀s of 38 and 13 nM for mouse and rat ABHD6^[1].

In Vitro

JW 618 (0.1-50 μM, 30 min) inhibits protein expression of MAGL and ABHD6 in mouse or rat brain proteomes^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1416133-88-4
Appearance Liquid
Masse moléculaire 392.30
Formule C₁₇H₁₄F₆N₂O₂
SMILES

O=C(N(CC1=CC(C2=CC=NC=C2)=CC=C1)C)OC(C(F)(F)F)C(F)(F)F
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Solution, -20°C, 2 years

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Chang JW, et al. Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates. Chem Biol. 2012 May 25;19(5):579-88. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
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JW 618

LEI-106

4-Nitrophenyl butyrate

DO-264

NG-497

Arachidoyl glycine

KT109

N-Arachidonyl maleimide

SAR629

FAAH-IN-9

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Bioz

JW 618

LEI-106

4-Nitrophenyl butyrate

DO-264

NG-497

Arachidoyl glycine

KT109

N-Arachidonyl maleimide

SAR629

FAAH-IN-9

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

JW 618 Related Classifications

HY-117722 Related Classifications

Bioz