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Cat. No.: HY-117722

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JW 618

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JW 618 is a selective ABHD6 inhibitor, with IC₅₀s of 38 and 13 nM for mouse and rat ABHD6.

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CAS No.: 1416133-88-4
Formule: C₁₇H₁₄F₆N₂O₂
Masse moléculaire:392.30

Stockage:

Solution, -20°C, 2 years

Data Sheet (265 KB)

JW 618 Chemical Structure

CAS No.: 1416133-88-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

JW 618 is a selective ABHD6 inhibitor, with IC₅₀s of 38 and 13 nM for mouse and rat ABHD6^[1].

In Vitro

JW 618 (0.1-50 μM, 30 min) inhibits protein expression of MAGL and ABHD6 in mouse or rat brain proteomes^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1416133-88-4
Appearance Liquid
Masse moléculaire 392.30
Formule C₁₇H₁₄F₆N₂O₂
SMILES

O=C(N(CC1=CC(C2=CC=NC=C2)=CC=C1)C)OC(C(F)(F)F)C(F)(F)F
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Solution, -20°C, 2 years

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Chang JW, et al. Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates. Chem Biol. 2012 May 25;19(5):579-88. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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