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Cat. No.: HY-P11269

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Lenbelintide

Lenbelintide is a dual amylin/calcitonin receptor agonist. Lenbelintide can be studied in research on obesity.

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CAS No.: 2793341-99-6
Formule: C₂₀₂H₃₁₉N₅₅O₆₃S₂
Masse moléculaire:4590.15

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Lenbelintide Chemical Structure

CAS No.: 2793341-99-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Lenbelintide is a dual amylin/calcitonin receptor agonist. Lenbelintide can be studied in research on obesity^[1].

In Vitro

Amylin receptors (AMYRs) are G protein-coupled receptors (GPCRs), which respond to the peptide hormones amylin and calcitonin. Amylin is originally discovered as the main constituent of pancreatic islet amyloid deposits in type 2 diabetics and in diabetic cats, amylin is also a physiologically relevant circulating peptide hormone. Amylin receptors are heterodimers comprising the calcitonin receptor, which is a G protein–coupled receptor, and one of three receptor-modifying proteins. An impediment to functional studies is that it is difficult to separate amylin receptor phenotypes from calcitonin receptor phenotypes. Amylin receptors are targets for treating obesity and metabolic disorders.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2793341-99-6
Masse moléculaire 4590.15
Formule C₂₀₂H₃₁₉N₅₅O₆₃S₂
Sequence

{Lys-(γGlu-γGlu-C18 diacid)}-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Arg-His-Ser-Ser-Asn-Asn-{(α-Me-Phe)}-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Glu-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (disulfide bridge:Cys2-Cys7)
Sequence Shortening

{Lys-(γGlu-γGlu-C18 diacid)}-CNTATCATQRLANFLRHSSNN-{(α-Me-Phe)}-GPILPPTEVGSNTY-NH2 (disulfide bridge:Cys2-Cys7)
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. WHO Drug Information, Vol. 39, No. 2, 2025

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

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100 mg

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