M 16209
M 16209 is an orally active aldose reductase (AR) inhibitor. M 16209 inhibits partially purified AR from various sources with IC50 values of 0.12, 0.24, 4.5, 1.2 and 9.3 μM for rat lens AR, bovine lens AR, bovine kidney AR, canine lens AR and human placental AR. M 16209 can be used for the research of metabolic disease, such as diabetes.
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- CAS No.: 128851-36-5
- Formule: C11H7BrN2O5S
- Masse moléculaire:359.15
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
M 16209 (10-30 mg/kg, p.o., daily for 14 days) ameliorates motor nerve conduction velocity delay in male Wistar rats with Streptozotocin (HY-13753)-induced diabetic neuropathy[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 128851-36-5
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Masse moléculaire 359.15
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Formule C11H7BrN2O5S
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SMILES
O=C1NC(CN1S(=O)(C2=C(Br)C3=CC=CC=C3O2)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
M 16209 Related Classifications
HY-101555 Related Classifications
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