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Cat. No.: HY-W780471

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MC 1080

MC 1080 is the main metabolite of MC 903 (Calcipotriol) (HY-10001). MC 1080 binds to the vitamin D receptor (1,25 (OH) 2D3 receptor). MC 1080 weakly induces differentiation of lymphoma cells but does not inhibit their proliferation at the highest concentration tested. MC 1080 can be used for research on histiocytic lymphoma.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 126860-84-2
Formule: C₂₇H₄₀O₃
Masse moléculaire:412.61

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (282 KB)

MC 1080 Chemical Structure

CAS No.: 126860-84-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

In Vitro

Anti-cancerOthers

Anti-cancer

MC 1080 weakly induces lymphoma cell differentiation but does not inhibit their proliferation at the highest concentration tested (100 nM)^[1].

Others

MC 1080 binds to the chicken intestinal 1,25 (OH)₂D₃ receptor, with a displacement rate of 50% at 1 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Cell Viability Determination by MTT Colorimetric Assay

Chemical Information

CAS No. 126860-84-2
Masse moléculaire 412.61
Formule C₂₇H₄₀O₃
SMILES

C[C@@]12[C@](\C(=C\C=C\3/C(=C)[C@@H](O)C[C@H](O)C3)\CCC1)(CC[C@@]2([C@@H](CCC(=O)C4CC4)C)[H])[H]
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (282 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Kissmeyer AM, et al. Calcipotriol (MC 903): pharmacokinetics in rats and biological activities of metabolites. A comparative study with 1,25(OH)2D3. Biochem Pharmacol. 1991 Jun 1;41(11):1601-6. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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