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Cat. No.: HY-169950

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NMDA agonist 1

NMDA agonist 1 (compound 42d) is a potent NMDA agonist with a K_i value of 96 nM. NMDA agonist 1 acts as a partial agonist of the GluN1/GluN2B complex with an EC₅₀ value of 78 nM.

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CAS No.: 2576586-47-3
Formule: C₁₂H₁₃N₃O₃S
Masse moléculaire:279.31

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

NMDA agonist 1 Chemical Structure

CAS No.: 2576586-47-3

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Chemical Information
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Description

NMDA agonist 1 (compound 42d) is a potent NMDA agonist with a K_i value of 96 nM. NMDA agonist 1 acts as a partial agonist of the GluN1/GluN2B complex with an EC₅₀ value of 78 nM^[1].

IC₅₀ & Target^[1]

NMDA Receptor

96 nM (Ki)

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Chemical Information

CAS No. 2576586-47-3
Masse moléculaire 279.31
Formule C₁₂H₁₃N₃O₃S
SMILES

O=C([C@@H](CNC(C1=CC2=NC=CC(C)=C2S1)=O)N)O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Ascic E, et al. Advancements in NMDA Receptor-Targeted Antidepressants: From d-Cycloserine Discovery to Preclinical Efficacy of Lu AF90103. J Med Chem. 2024 Nov 28;67(22):20135-20155. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Pureté et documentation
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NMDA agonist 1

Voir tous les produits spécifiques à Isoform iGluR

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

NMDA agonist 1 Related Classifications

HY-169950 Related Classifications