NOS-IN-3
NOS-IN-3 (Compound 9a) is a potent, selective, imidamide derived NOS inhibitor with an IC50 against iNOS of 4.6 μM, without inhibiting eNOS. NOS-IN-3 has little toxicity and can be studied in the research of inducible isoform involved diseases, such as septic shock.
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- CAS No.: 2761725-68-0
- Formule: C10H15N3O
- Masse moléculaire:193.25
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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iNOS |
nNOS |
NOS-IN-3 (Compound 9a) shows high iNOS selectivity without eNOS inhibition activity [1].
NOS-IN-3 (0-100 µM, 30 min) has little toxicity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HUVECs
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Concentration:10, 20, 50, 100, 500 µM
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Incubation Time:30 min
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Result:Had little toxicity, only at the concentration above 100 µM, the cell viability was significantly (approximately 20%) reduced.
Chemical Information
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CAS No. 2761725-68-0
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Masse moléculaire 193.25
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Formule C10H15N3O
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SMILES
CC(NCCC(C1=CC=CN=C1)O)=N
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NOS-IN-3 Related Classifications
HY-115917 Related Classifications
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