NOX2-IN-2 diTFA
Based on 1 Customer Validation
NOX2-IN-2 diTFA (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. NOX2-IN-2 diTFA inhibits ROS production derived from NOX2 in cells.
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- Pureté: 98.15%
- CAS No.: 2648709-80-0
- Formule: C29H27F6N7O7
- Masse moléculaire:699.56
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Stockage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Activité biologique
Chemical Information
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CAS No. 2648709-80-0
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Appearance Solid
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Masse moléculaire 699.56
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Formule C29H27F6N7O7
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Color White to off-white
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SMILES
NC1=NC2=CC=C(C=C2C=C1)OCC3=CN(N=N3)CCOCCOC4=CC=C5N=C(C=CC5=C4)N.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
DMSO : 125 mg/mL (178.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4295 mL | 7.1473 mL | 14.2947 mL | 35.7367 mL |
| 5 mM | 0.2859 mL | 1.4295 mL | 2.8589 mL | 7.1473 mL | |
| 10 mM | 0.1429 mL | 0.7147 mL | 1.4295 mL | 3.5737 mL | |
| 15 mM | 0.0953 mL | 0.4765 mL | 0.9530 mL | 2.3824 mL | |
| 20 mM | 0.0715 mL | 0.3574 mL | 0.7147 mL | 1.7868 mL | |
| 25 mM | 0.0572 mL | 0.2859 mL | 0.5718 mL | 1.4295 mL | |
| 30 mM | 0.0476 mL | 0.2382 mL | 0.4765 mL | 1.1912 mL | |
| 40 mM | 0.0357 mL | 0.1787 mL | 0.3574 mL | 0.8934 mL | |
| 50 mM | 0.0286 mL | 0.1429 mL | 0.2859 mL | 0.7147 mL | |
| 60 mM | 0.0238 mL | 0.1191 mL | 0.2382 mL | 0.5956 mL | |
| 80 mM | 0.0179 mL | 0.0893 mL | 0.1787 mL | 0.4467 mL | |
| 100 mM | 0.0143 mL | 0.0715 mL | 0.1429 mL | 0.3574 mL |