NSC309401
NSC309401 is an inhibitor of E. coli DHFR (IC50: 189 nM, KD: 14.57 nM).
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- CAS No.: 750522-61-3
- Formule: C17H16N6
- Masse moléculaire:304.35
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
189 nM (E. coli DHFR)[1].
Chemical Information
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CAS No. 750522-61-3
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Masse moléculaire 304.35
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Formule C17H16N6
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SMILES
NC(C=C1)=CC=C1CN2C=CC3=C4C(N=C(N)N=C4N)=CC=C32
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Srinivasan B, et al. Insights into the slow-onset tight-binding inhibition of Escherichia coli dihydrofolate reductase: detailed mechanistic characterization of pyrrolo [3,2-f] quinazoline-1,3-diamine and its derivatives as novel tight-binding inhibitors. FEBS J. 2015 May;282(10):1922-38. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NSC309401 Related Classifications
HY-156859A Related Classifications
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