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Cat. No.: HY-106580A

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Plafibride hydrochloride

(Synonyms: ITA 104 hydrochloride)

Plafibride hydrochloride (ITA 104 hydrochloride) is an orally active hypolipemic, platelet aggregation inhibitor.

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CAS No.: 65285-81-6
Formule: C₁₆H₂₃Cl₂N₃O₄
Masse moléculaire:392.28

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Plafibride hydrochloride Chemical Structure

CAS No.: 65285-81-6

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Activité biologique
- Description
- In Vivo
Chemical Information
Pureté et documentation
Références
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Activité biologique

Description

Plafibride hydrochloride (ITA 104 hydrochloride) is an orally active hypolipemic, platelet aggregation inhibitor^[1]^[2].

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Retinol Binding Protein

In Vivo

Plafibride (100 mg/kg, p.o.) hydrochloride shows marked platelet anti-aggregant activity in rabbits^[1].
Plafibride hydrochloride has low toxicity, with LD₅₀s of about 4000 mg/kg (p.o.) in rat, mouse and hamster^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Rabbit^[1]
Dosage:

100 mg/kg
Administration:

Oral administration (p.o.)
Result:

Induced platelet aggregation.

Chemical Information

CAS No. 65285-81-6
Masse moléculaire 392.28
Formule C₁₆H₂₃Cl₂N₃O₄
SMILES

O=C(NCN1CCOCC1)NC(C(C)(C)OC2=CC=C(C=C2)Cl)=O.Cl
Synonyms

ITA 104 hydrochloride
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. L Bruseghini, et al. Platelet antiaggregant activity of plafibride ex vivo in rat, dog and rabbit. Arzneimittelforschung. 1981;31(10a):1790-5. [Content Brief]

[2]. J Zapatero, et al. Toxicological studies of plafibride. Part 1: Acute toxicity and its determination after several administrations of plafibride. Arzneimittelforschung. 1981;31(10a):1816-9. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Plafibride hydrochloride

Voir tous les produits spécifiques à Isoform Lipocalin Family

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Plafibride hydrochloride Related Classifications

HY-106580A Related Classifications