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Cat. No.: HY-170350

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Pomalidomide-PEG2-OMs

Pomalidomide-PEG2-Oms (CRBN ligand Pomalidomide (HY-10984)) is an E3 Ligase Ligand-Linker Conjugate for EGFR PROTAC DDC-01-163 (HY-139997).

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CAS No.: 2140807-37-8
Formule: C₂₀H₂₅N₃O₉S
Masse moléculaire:483.49

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Pomalidomide-PEG2-OMs Chemical Structure

CAS No.: 2140807-37-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Pomalidomide-PEG2-Oms (CRBN ligand Pomalidomide (HY-10984)) is an E3 Ligase Ligand-Linker Conjugate for EGFR PROTAC DDC-01-163 (HY-139997)^[1].

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Chemical Information

CAS No. 2140807-37-8
Masse moléculaire 483.49
Formule C₂₀H₂₅N₃O₉S
SMILES

O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOS(=O)(C)=O)=CC=C3)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Jaebong Jang, et al. Mutant-Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug-Resistant Mutations. Angew Chem Int Ed Engl. 2020 Aug 17;59(34):14481-14489. [Content Brief]

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Pomalidomide-PEG2-OMs

Voir tous les produits spécifiques à Isoform E3 Ligase Ligand-Linker Conjugates

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Pomalidomide-PEG2-OMs Related Classifications

HY-170350 Related Classifications

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Keywords

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