RXR agonist 3
RXR agonist 3 (Compound 35) is a potent, partial RXR agonist (EC50s: 3, 3, 8 nM for RXRα, RXRβ, RXRγ, respectively). RXR agonist 3 can be used in the research of Alzheimer's disease, multiple sclerosis, and lymphoma.
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- Formule: C19H21F3N4O2
- Masse moléculaire:394.39
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
RXR α 3 nM (EC50) |
RXRβ 3 nM (EC50) |
RXRγ 8 nM (EC50) |
Chemical Information
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Masse moléculaire 394.39
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Formule C19H21F3N4O2
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SMILES
OC(CCNC1=NC(N2CCC(C)(C3=C2C=CC=C3)C)=CC(C(F)(F)F)=N1)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RXR agonist 3 Related Classifications
HY-180182 Related Classifications
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