Sertindole (Standard)
Sertindole (Standard) is the analytical standard of Sertindole. This product is intended for research and analytical applications. Sertindole (Lu 23-174) is an orally active 5-HT2A, 5-HT2C, dopamine D2, and αl-adrenergic receptors antagonist. Sertindole shows antipsychotic activity and anti-proliferative activity to multiple cancer cells.
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- CAS No.: 106516-24-9
- Formule: C24H26ClFN4O
- Masse moléculaire:440.94
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 106516-24-9
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Masse moléculaire 440.94
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Formule C24H26ClFN4O
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SMILES
FC1=CC=C(N2C3=CC=C(Cl)C=C3C(C4CCN(CCN5CCNC5=O)CC4)=C2)C=C1
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Synonyms
Lu 23-174 (Standard)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. David Murdoch, et al. Sertindole : a review of its use in schizophrenia. CNS Drugs. 2006;20(3):233-55. [Content Brief]
[2]. Wei Zhang, et al. Antiproliferative activities of the second-generation antipsychotic drug sertindole against breast cancers with a potential application for treatment of breast-to-brain metastases. Sci Rep. 2018 Oct 25;8(1):15753. [Content Brief]
[3]. Mario F Juruena, et al. Sertindole in the management of schizophrenia. J Cent Nerv Syst Dis. 2011 May 17;3:75-85. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Sertindole (Standard)
- 106516-24-9
- Lu 23-174 (Standard)
- 5-HT Receptor
- Dopamine Receptor
- Adrenergic Receptor
- Autophagy
- Reference Standards
- antipsychotic activity
- anti-proliferative activity
- MCF-10A
- NCI-H460
- A549
- NCI-H446
- NCI-H661
- 801-D
- U251
- A172
- U118-MG
- U87-MG
- AGS
- MKN45
- BGC-823
- SGC-7901
- HT-29
- COLO205
- SW480
- SW620
- HCT-15
- HepG2
- Bel-7402
- MCF-7
- MDA-MB-231
- SUM159
- T47D
- MDA-MB-453
- ZR-75-1
- CCRF-CEM
- K562
- Jurkat
- Inhibitor
- inhibitor
- inhibit