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Cat. No.: HY-182451

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V11294

V11294 is a phosphodiesterase 4 (PDE4) inhibitor with a K_i value of 436 nM against human lung PDE4. V11294 exhibits anti-inflammation activity.

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CAS No.: 162278-10-6
Formule: C₂₃H₃₁N₅O₂
Masse moléculaire:409.52

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Please store the product under the recommended conditions in the Certificate of Analysis.

V11294 Chemical Structure

CAS No.: 162278-10-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

V11294 is a phosphodiesterase 4 (PDE4) inhibitor with a K_i value of 436 nM against human lung PDE4. V11294 exhibits anti-inflammation activity^[1].

IC₅₀ & Target^[1]

hPDE4D

436 nM (Ki)

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE) :

In Vitro

V11294 (Compound 34) selectively inhibits human lung hPDE4 with a K_i of 436 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 162278-10-6
Masse moléculaire 409.52
Formule C₂₃H₃₁N₅O₂
SMILES

CCNC1=C2N=C(C(C)C)N=C2N(CC3=CC=C(C(OC4CCCC4)=C3)OC)C=N1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Kodimuthali A, et al. Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease. J Med Chem. 2008 Sep 25;51(18):5471-89. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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V11294

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE)