ZW290
Based on 1 Customer Validation
ZW290 is a compound to activate brown adipose tissue (BAT) thermogenic function. ZW290 increases the expression of uncoupling Protein 1 (UCP1) protein and inhibits ATP synthesis in BAT.
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- Pureté: 99.60%
- CAS No.: 2411852-67-8
- Formule: C20H18N2O6S
- Masse moléculaire:414.43
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Covalent Screening Library
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Mitochondria-Targeted Compound Library
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Glucose Metabolism Compound Library
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Bioactive Compound Library Max
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MCE Bioactive Compound Library
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Covalent Screening Library Plus
HY-L036P
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Bioactive Compound Library
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High-Throughput Bioactive Compound Library
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Activité biologique
ZW290 in brown adipose tissue (BAT) induces nonshivering thermogenesis by limiting the oxidation of lipid droplet-derived fatty acids and increasing UCP1 protein levels[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Kunming (KM) mice (20 g) keeping under acute cold exposure (-20°C)[1]
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Dosage:25 mg/kg, 50 mg/kg, or 100 mg/kg
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Administration:Oral gavage; once a day; for 7 days
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Result:Notably decreased the size of lipid droplets in BAT and increased the content of mitochondria and the expression of UCP1 in BAT and WAT.
Chemical Information
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CAS No. 2411852-67-8
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Appearance Solid
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Masse moléculaire 414.43
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Formule C20H18N2O6S
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Color Yellow to brown
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SMILES
O=C1N(C2=CC=C(C=C2)OC)C(N/C1=C\C3=CC(OC)=C(C=C3)OCC(O)=O)=S
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureté et documentation
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Fiche technique (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ZW290 Related Classifications
HY-148973 Related Classifications
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