10045-45-1
Chemical Structure
1-EBIO
Synonym(s): 1-Ethyl-2-benzimidazolinone
- CAS No.: 10045-45-1
- Formula:C9H10N2O
- Molecular Weight:162.19
IUPAC Name: 1-ethyl-1,3-dihydro-2H-benzo[d]imidazol-2-one
InChIKey: CXUCKELNYMZTRT-UHFFFAOYSA-N
SMILES: O=C1NC2=CC=CC=C2N1CC
Biological Activity: 1-EBIO is an activator of Ca2+ sensitive K+ channels. 1-EBIO is used to study the role of K+ channels in diverse physiological functions[1].
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1-EBIO | 99.96% | 1-EBIO is an activator of Ca2+ sensitive K+ channels. 1-EBIO is used to study the role of K+ channels in diverse physiological functions. | ||||||||||||||||||||
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1-EBIO (Standard) | ≥98% | 1-EBIO (1-Ethyl-2-benzimidazolinone) (Standard) is the analytical standard of 1-EBIO (HY-101360). This product is intended for research and analytical applications. 1-EBIO is an activator of Ca2+ sensitive K+ channels wirh an EC50 of 136 μM for KCa3.1. 1-EBIO induces Cl- secretion, K+ conductance, membrane hyperpolarization, and afterhyperpolarisation currents. 1-EBIO reduces epileptiform activity, seizure incidence, and rescues cells from Ionomycin (HY-13434)-induced death. | ||||||||||||||||||||
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Keywords