1005342-46-0
1005342-46-0
Chemical Structure
LCL161
- CAS. Nr.: 1005342-46-0
- Formula:C26H33FN4O3S
- Molecular Weight:500.63
IUPAC Name: (S)-N-((S)-1-cyclohexyl-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)propanamide
InChIKey: UFPFGVNKHCLJJO-SSKFGXFMSA-N
SMILES: C[C@H](NC)C(N[C@@H](C1CCCCC1)C(N2[C@H](C3=NC(C(C4=CC=C(F)C=C4)=O)=CS3)CCC2)=O)=O
Biological Activity: LCL161 is a IAP inhibitor which inhibits XIAP in HEK293 cell and cIAP1 in MDA-MB-231 cell with IC50s of 35 and 0.4 nM, respectively.
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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LCL161 | 99.91% | LCL161 is a IAP inhibitor which inhibits XIAP in HEK293 cell and cIAP1 in MDA-MB-231 cell with IC50s of 35 and 0.4 nM, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.87
HY-176441E3 ligase Ligand 66 -
Similarity Score 0.73
HY-128808cIAP1 ligand 1 -
Similarity Score 0.72
HY-139999LCL-PEG3-N3 -
Similarity Score 0.72
HY-139999ALCL-PEG3-N3 hydrochloride -
Similarity Score 0.69
HY-128809cIAP1 ligand 2 -
Similarity Score 0.64
HY-128818cIAP1 Ligand-Linker Conjugates 5 -
Similarity Score 0.62
HY-128819cIAP1 Ligand-Linker Conjugates 3 -
Similarity Score 0.60
HY-128820cIAP1 Ligand-Linker Conjugates 1 -
Similarity Score 0.56
HY-155019Anticancer agent 128 -
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