1020719-42-9
Chemical Structure
Famciclovir-d4
Synonym(s): BRL 42810-d4
- CAS No.: 1020719-42-9
- Formula:C14H15D4N5O4
- Molecular Weight:325.36
IUPAC Name: 2-(2-(2-amino-9H-purin-9-yl)ethyl-1,1,2,2-d4)propane-1,3-diyl diacetate
InChIKey: GGXKWVWZWMLJEH-KHORGVISSA-N
SMILES: CC(OCC(COC(C)=O)C([2H])([2H])C([2H])([2H])N1C2=NC(N)=NC=C2N=C1)=O
Biological Activity: Famciclovir-d4 is the deuterium labeled Famciclovir. Famciclovir (BRL 42810) is a guanine analogue antiviral agent used for the treatment of various herpesvirus infections[1][2].
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Famciclovir-d4 | Famciclovir-d4 is the deuterium labeled Famciclovir. Famciclovir (BRL 42810) is a guanine analogue antiviral agent used for the treatment of various herpesvirus infections. | |||||||||||||||||||||
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Famciclovir (Standard) | ≥98% | Famciclovir (Standard) is the analytical standard of Famciclovir. This product is intended for research and analytical applications. Famciclovir (BRL 42810) is an orally active nucleoside analogue. Famciclovir is an antiviral agent with potent activities against HBV, HSV and VZV. Famciclovir can be used for the research of herpesvirus infection. | ||||||||||||||||||||
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Famciclovir-d6 | Famciclovir-d6 (BRL 42810-d6) is deuterium labeled Famciclovir. Famciclovir (BRL 42810) is an orally active nucleoside analogue. Famciclovir is an antiviral agent with potent activities against HBV, HSV and VZV. Famciclovir can be used for the research of herpesvirus infection. | |||||||||||||||||||||
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Famciclovir | 99.40% | Famciclovir (BRL 42810) is an orally active nucleoside analogue. Famciclovir is an antiviral agent with potent activities against HBV, HSV and VZV. Famciclovir can be used for the research of herpesvirus infection. | ||||||||||||||||||||
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Similarity Score 0.82
HY-W102361R2-(2-(2-Amino-6-chloro-9H-purin-9-yl)ethyl)propane-1,3-diyl diacetate (Standard) -
Similarity Score 0.76
HY-Z44836-Deoxypenciclovir -
Similarity Score 0.72
HY-147015HOE961 -
Similarity Score 0.69
HY-106175Detiviciclovir -
Similarity Score 0.66
HY-159737Rociclovir -
Similarity Score 0.65
HY-162069Antiviral agent 47 -
Similarity Score 0.64
HY-107739Penciclovir sodium -
Similarity Score 0.63
HY-17424Penciclovir -
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Harrell AW, Wheeler SM, Pennick M, Evidence that famciclovir (BRL 42810) and its associated metabolites do not inhibit the 6 beta-hydroxylation of testosterone in human liver microsomes. Drug Metab Dispos. 1993 Jan-Feb;21(1):18-23. [Content Brief]