10219-69-9
10219-69-9
Chemical Structure
(R)-Coriolic acid
Synonym(s): 13(R)-HODE
- CAS No.: 10219-69-9
- Formula:C18H32O3
- Molecular Weight:296.44
IUPAC Name: (R,9Z,11E)-13-hydroxyoctadeca-9,11-dienoic acid
InChIKey: HNICUWMFWZBIFP-PIHGWCCBSA-N
SMILES: CCCCC[C@@H](O)/C=C/C=C\CCCCCCCC(O)=O
Biological Activity: 13(R)-HODE is the opposite enantiomer of the 13(S)-HODE produced when linoleic acid is incubated with soybean lipoxygenase. The presence of 13(R)-HODE in the supernatants and membranes of cultured bovine endothelial cells has been attributed to COX metabolism.1 13(R)-HODE is a weak (IC50=2.7 μM) inhibitor of U-46619-induced platelet aggregation.
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(R)-Coriolic acid | 13(R)-HODE is the opposite enantiomer of the 13(S)-HODE produced when linoleic acid is incubated with soybean lipoxygenase. The presence of 13(R)-HODE in the supernatants and membranes of cultured bovine endothelial cells has been attributed to COX metabolism.1 13(R)-HODE is a weak (IC50=2.7 μM) inhibitor of U-46619-induced platelet aggregation. | |||||||||||||||||||||
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