1031336-60-3
1031336-60-3
Chemical Structure
ABT-046
- CAS No.: 1031336-60-3
- Formula:C20H22N4O2
- Molecular Weight:350.41
IUPAC Name: 2-((1r,4r)-4-(4-(7-aminopyrazolo[1,5-a]pyrimidin-6-yl)phenyl)cyclohexyl)acetic acid
InChIKey: BWUXSHHOKODNAK-HDJSIYSDSA-N
SMILES: NC1=C(C2=CC=C([C@H]3CC[C@H](CC(O)=O)CC3)C=C2)C=NC4=CC=NN41
Biological Activity: ABT-046 is a potent, selective, and orally active acyl CoA:diacylglycerol acyltransferase 1 (DGAT-1) inhibitor with IC50s of both 8 nM against human and mouse DGAT-1[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ABT-046 | 98.57% | ABT-046 is a potent, selective, and orally active acyl CoA:diacylglycerol acyltransferase 1 (DGAT-1) inhibitor with IC50s of both 8 nM against human and mouse DGAT-1. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.57
HY-113673A-935142 -
Similarity Score 0.51
HY-114199Eph inhibitor 1 -
Similarity Score 0.50
HY-131005Eph inhibitor 2 -
Similarity Score 0.49
HY-783972-((1s,4s)-4-Phenylcyclohexyl)acetic acid -
Similarity Score 0.49
HY-123141K00135 -
Similarity Score 0.47
HY-148742RET-IN-21 -
Similarity Score 0.47
HY-136534RET V804M-IN-1 -
Similarity Score 0.46
HY-139628JPD447 -
Similarity Score 0.46
HY-113745LX-6171 -
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