104076-38-2
104076-38-2
Chemical Structure
Zolantidine
Synonym(s): SK&F 95282
- CAS No.: 104076-38-2
- Formula:C22H27N3OS
- Molecular Weight:381.53
IUPAC Name: N-(3-(3-(piperidin-1-ylmethyl)phenoxy)propyl)benzo[d]thiazol-2-amine
InChIKey: KUBONGDXTUOOLM-UHFFFAOYSA-N
SMILES: C1(NCCCOC2=CC=CC(CN3CCCCC3)=C2)=NC4=CC=CC=C4S1
Biological Activity: Zolantidine (SKF 95282) is a potent, selective and cross the blood-brain barrier histamine H2 antagonist. Zolantidine induces antinociception[1][2].
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Zolantidine | Zolantidine (SKF 95282) is a potent, selective and cross the blood-brain barrier histamine H2 antagonist. Zolantidine induces antinociception. | |||||||||||||||||||||
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References
- [1]. Calcutt CR, et al. Zolantidine (SK&F 95282) is a potent selective brain-penetrating histamine H2-receptor antagonist. Br J Pharmacol. 1988 Jan;93(1):69-78. [Content Brief]
- [2]. Hasanein P. Two histamine H2 receptor antagonists, zolantidine and cimetidine, modulate nociception in cholestatic rats. J Psychopharmacol. 2011 Feb;25(2):281-8. [Content Brief]
Keywords
