1065-31-2
Chemical Structure
Coenzyme Q6
Synonym(s): Ubiquinone 30
- CAS No.: 1065-31-2
- Formula:C39H58O4
- Molecular Weight:590.88
IUPAC Name: 2-((2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
InChIKey: GXNFPEOUKFOTKY-LPHQIWJTSA-N
SMILES: C/C(C)=C\CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC(C(C(OC)=C1OC)=O)=C(C)C1=O
Biological Activity: Coenzyme Q6 (Ubiquinone 30) is a redox-active benzoquinone lipid and mitochondrial electron carrier. Coenzyme Q6 can be used in research on MASLD, mitochondrial diseases, pneumococcal diseases, and steroid-resistant nephrotic syndrome with FSGS[1][2][3][4][5].
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Coenzyme Q6 | Coenzyme Q6 (Ubiquinone 30) is a redox-active benzoquinone lipid and mitochondrial electron carrier. Coenzyme Q6 can be used in research on MASLD, mitochondrial diseases, pneumococcal diseases, and steroid-resistant nephrotic syndrome with FSGS. | |||||||||||||||||||||
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References
- [1]. Jakhmola V, et al. Java Plum-Derived Extracellular Vesicles Modulate Gut Microbiota and Enhance Hepatic Mitochondrial Bioenergetics to Ameliorate Steatosis in MASLD.
- [2]. Ernster L, et al. Ubiquinol: an endogenous antioxidant in aerobic organisms. The Clinical investigator. 1993;71(8 Suppl):S60-5.
- [3]. Santos-Ocaña C, et al. Coenzyme Q6 and iron reduction are responsible for the extracellular ascorbate stabilization at the plasma membrane of Saccharomyces cerevisiae. The Journal of biological chemistry. 1998 Apr 03;273(14):8099-105.
- [4]. Walker EC, et al. Novel coenzyme Q6 genetic variant increases susceptibility to pneumococcal disease. Nature immunology. 2024 Dec;25(12):2247-2258.
- [5]. Widmeier E, et al. Treatment with 2,4-Dihydroxybenzoic Acid Prevents FSGS Progression and Renal Fibrosis in Podocyte-Specific Knockout Mice. Journal of the American Society of Nephrology : JASN. 2019 Mar;30(3):393-405. [Content Brief]
