108787-91-3
108787-91-3
Chemical Structure
Boc3Arg
- CAS No.: 108787-91-3
- Formula:C21H38N4O8
- Molecular Weight:474.55
IUPAC Name: (S)-2-((tert-butoxycarbonyl)amino)-5-((2,2,10,10-tetramethyl-4,8-dioxo-3,9-dioxa-5,7-diazaundecan-6-ylidene)amino)pentanoic acid
InChIKey: BGOFOVHACSQSIE-ZDUSSCGKSA-N
SMILES: O=C(O)[C@H](CCC/N=C(NC(OC(C)(C)C)=O)/NC(OC(C)(C)C)=O)NC(OC(C)(C)C)=O
Biological Activity: Boc3Arg is the tert-butyl carbamate-protected arginine. Boc3Arg is an efficient tag to induce degradation through directly localizing the protein to the 20S proteasome[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Boc3Arg | 97.0% | Boc3Arg is the tert-butyl carbamate-protected arginine. Boc3Arg is an efficient tag to induce degradation through directly localizing the protein to the 20S proteasome. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.75
HY-W088151Boc-Arg(Boc)2-OH -
Similarity Score 0.68
HY-W007599(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid -
Similarity Score 0.68
HY-W018528N2,N6-Bis(tert-butoxycarbonyl)-D-lysine -
Similarity Score 0.63
HY-W009229Boc-Glu(OtBu)-OH -
Similarity Score 0.61
HY-W047799Boc-Dap(Boc)-OH -
Similarity Score 0.61
HY-W013734N,N'-Di-BOC-L-cystine -
Similarity Score 0.60
HY-W013810(tert-Butoxycarbonyl)-L-arginine hydrochloride -
Similarity Score 0.60
HY-W101935N-Boc-D-Arg hydrochloride -
Similarity Score 0.60
HY-W013305(S)-2-((tert-Butoxycarbonyl)amino)-5-guanidinopentanoic acid -
Explore the MedChemAI to find more analogs
References
- [1]. Sun H, et al. Identification of Boc2Lys-Linked Ethacrynic Acid and Its Analogues As Efficient Glutathione S-Transferase Degraders. ACS Med Chem Lett. 2024 Oct 14;15(11):1852-1859. [Content Brief]
- [2]. Marcus J.C. Long, et al. Inhibitor Mediated Protein Degradation. Chemistry & Biology. 2021, 19 (5): 629-637.
