11032-98-7
Chemical Structure
Desmycosin
- CAS. Nr.: 11032-98-7
- Formula:C39H65NO14
- Molecular Weight:771.93
IUPAC Name: 2-((4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-16-ethyl-4-hydroxy-15-((((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)-5,9,13-trimethyl-2,10-dioxooxacyclohexadeca-11,13-dien-7-yl)acetaldehyde
InChIKey: QRPHLEPFYLNRDA-NLGRAQRVSA-N
SMILES: O=CC[C@@H](C[C@H](C(/C=C/C(C)=C/[C@@H]([C@H](OC(C[C@H]([C@@H]1C)O)=O)CC)CO[C@H]2[C@@H]([C@@H]([C@@H]([C@H](O2)C)O)OC)OC)=O)C)[C@@H]1O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C)O)N(C)C)O
Biological Activity: Desmycosin is a macrolide antibiotic. Desmycosin exhibits biological activity against H. influenzae, S.aureus, S. pneumoniae, and S. pyogenes with MIC values of 4, 1, <0.125, and <0.125 µg/ml, respectively. Desmycosin is an acidic degradation product of tylosin[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Desmycosin | 95.00% | Desmycosin is a macrolide antibiotic. Desmycosin exhibits biological activity against H. influenzae, S.aureus, S. pneumoniae, and S. pyogenes with MIC values of 4, 1, <0.125, and <0.125 µg/ml, respectively. Desmycosin is an acidic degradation product of tylosin. | ||||||||||||||||||||
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References
- [1]. Iveković D, et al., Electrochemical reduction of desmycosin, structure investigation and antibacterial evaluation of the resulting products. Eur J Pharm Sci. 2003 Apr;18(5):323-8. [Content Brief]
- [2]. Thompson TS, et al., Tylosin A and desmycosin in honey by salting-out assisted liquid-liquid extraction and aqueous normal phase ultraperformance liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2019 Sep;411(24):6509-6518. [Content Brief]
