110657-98-2
Chemical Structure
Lipoxin A5
- CAS No.: 110657-98-2
- Formula:C20H30O5
- Molecular Weight:350.45
IUPAC Name: (5S,6R,7E,9E,11Z,13E,15S,17Z)-5,6,15-trihydroxyicosa-7,9,11,13,17-pentaenoic acid
InChIKey: ZZMKOZNTEJVKRY-YJUORNCYSA-N
SMILES: OC(CCC[C@H](O)[C@H](O)/C=C/C=C/C=C\C=C\[C@@H](O)C/C=C\CC)=O
Biological Activity: Lipoxin A5 is an eicosapentaenoic acid derived from pig white blood cells. Lipoxin A5 slowly contracted the guinea pig lung parenchymal strips with a contractile force similar to that of LXA4 and LXB4.2, but LXA5 did not have the vasodilating effect on the aortic smooth muscle shown by LXA4 and LXB4.2[1][2].
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Lipoxin A5 | Lipoxin A5 is an eicosapentaenoic acid derived from pig white blood cells. Lipoxin A5 slowly contracted the guinea pig lung parenchymal strips with a contractile force similar to that of LXA4 and LXB4.2, but LXA5 did not have the vasodilating effect on the aortic smooth muscle shown by LXA4 and LXB4.2. | |||||||||||||||||||||
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- [1]. Wong PY, et al. Lipoxene: a new group of trihydroxy pentaenes of eicosapentaenoic acid derived from porcine leukocytes. Biochem Biophys Res Commun. 1985 Jan 31;126(2):763-72. [Content Brief]
- [2]. Stahl GL, et al. Pharmacologic profile of lipoxins A5 and B5: new biologically active eicosanoids. Eur J Pharmacol. 1989 Apr 12;163(1):55-60. [Content Brief]
Keywords
