114590-20-4
Chemical Structure
Soyasaponin Ba
- CAS No.: 114590-20-4
- Formula:C48H78O19
- Molecular Weight:959.12
IUPAC Name: (2S,3S,4S,5R,6R)-5-(((2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(((3S,4S,4aR,6aR,6bS,8aR,9R,12aS,14aR,14bR)-9-hydroxy-4-(hydroxymethyl)-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
InChIKey: WFRQIKSNAYYUJZ-BKQVBUAGSA-N
SMILES: O[C@H]([C@H]1O[C@@]2([H])[C@H](O[C@]3([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@@H](O)[C@@H](CO)O2)[C@H](O)[C@@H](C(O)=O)O[C@@]1([H])O[C@@H]4[C@@](CO)(C)[C@]5([H])CC[C@@]6(C)[C@]7(C)CC[C@@]8(C)[C@H](O)CC(C)(C)C[C@@]8([H])C7=CC[C@]6([H])[C@@]5(C)CC4
Biological Activity: Soyasaponin Ba is a soyasaponin that can be isolated from Phaseolus vulgaris, acts as an aldose reductase inhibitor (ARI). Soyasaponin Ba activates Akt/GSK3β/β-catenin signaling pathway, reduces lipid accumulation, lowers ROS generation, improves mitochondrial membrane potential, ATP levels, and morphology, and inhibits apoptosis. Soyasaponin Ba can be used for the research of lipid accumulation and secondary diabetic complications[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Soyasaponin Ba | 99.47% | Soyasaponin Ba is a soyasaponin that can be isolated from Phaseolus vulgaris, acts as an aldose reductase inhibitor (ARI). Soyasaponin Ba activates Akt/GSK3β/β-catenin signaling pathway, reduces lipid accumulation, lowers ROS generation, improves mitochondrial membrane potential, ATP levels, and morphology, and inhibits apoptosis. Soyasaponin Ba can be used for the research of lipid accumulation and secondary diabetic complications. | ||||||||||||||||||||
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Soyasaponin Ba (Standard) | ≥98% | Soyasaponin Ba (Standard) is the analytical standard of Soyasaponin Ba (HY-N0309). Soyasaponin Ba is a soyasaponin that can be isolated from Phaseolus vulgaris, acts as an aldose reductase inhibitor (ARI). Soyasaponin Ba activates Akt/GSK3β/β-catenin signaling pathway, reduces lipid accumulation, lowers ROS generation, improves mitochondrial membrane potential, ATP levels, and morphology, and inhibits apoptosis. Soyasaponin Ba can be used for the research of lipid accumulation and secondary diabetic complications. | ||||||||||||||||||||
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Similarity Score 0.95
HY-N0310RSoyasaponin Bb (Standard) -
Similarity Score 0.89
HY-107302Sandosaponin A -
Similarity Score 0.89
HY-123700Kaikasaponin III -
Similarity Score 0.89
HY-N13145Azukisaponin II -
Similarity Score 0.89
HY-N7273Soyasaponin III -
Similarity Score 0.88
HY-122920Soyasaponin II -
Similarity Score 0.87
HY-N20621Subproside V -
Similarity Score 0.85
HY-N20620Subproside IV -
Similarity Score 0.84
HY-N19857Millettiasaponin A -
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References
- [1]. Luo J, et al. Soyasaponin Ba Alleviates Lipid Accumulation via Mitochondrial Remodeling: Multiomics Insights. J Agric Food Chem. 2025;73(33):21199-21221. [Content Brief]
- [2]. Balestri F, et al. Soyasaponins from Zolfino bean as aldose reductase differential inhibitors. J Enzyme Inhib Med Chem. 2019;34(1):350-360. [Content Brief]
