115256-11-6
115256-11-6
Chemical Structure
Dofetilide
Synonym(s): UK 68789
- CAS No.: 115256-11-6
- Formula:C19H27N3O5S2
- Molecular Weight:441.56
IUPAC Name: N-(4-(2-(methyl(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)ethyl)phenyl)methanesulfonamide
InChIKey: IXTMWRCNAAVVAI-UHFFFAOYSA-N
SMILES: CS(=O)(NC1=CC=C(CCN(C)CCOC2=CC=C(NS(=O)(C)=O)C=C2)C=C1)=O
Biological Activity: Dofetilide (UK 68789), as a class III antiarrhythmic agent, is an orally active, potent and specific IKr blocker. Dofetilide can be used for the research of cardiovascular disease[1][2].
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Dofetilide | 98.84% | Dofetilide (UK 68789), as a class III antiarrhythmic agent, is an orally active, potent and specific IKr blocker. Dofetilide can be used for the research of cardiovascular disease. | ||||||||||||||||||||
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Dofetilide (Standard) | ≥98% | Dofetilide (Standard) is the analytical standard of Dofetilide. This product is intended for research and analytical applications. Dofetilide (UK 68789), as a class III antiarrhythmic agent, is an orally active, potent and specific IKr blocker. Dofetilide can be used for the research of cardiovascular disease. | ||||||||||||||||||||
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Dofetilide-d4 | 99.25% | Dofetilide-d4 is a deuterium labeled Dofetilide. Dofetilide is a class III antiarrhythmic agent. | ||||||||||||||||||||
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References
- [1]. Mounsey JP, et al. Cardiovascular drugs. Dofetilide. Circulation. 2000;102(21):2665-2670. [Content Brief]
- [2]. Gwilt M, et al. Dofetilide, a new class III antiarrhythmic agent, reduces pacing induced heterogeneity of repolarisation in vivo. Cardiovasc Res. 1992;26(11):1102-1108. [Content Brief]
