1159600-41-5
Chemical Structure
Basmisanil
Synonym(s): RG1662; RO5186582
- CAS No.: 1159600-41-5
- Formula:C21H20FN3O5S
- Molecular Weight:445.46
IUPAC Name: (1,1-dioxidothiomorpholino)(6-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)pyridin-3-yl)methanone
InChIKey: VCGRFBXVSFAGGA-UHFFFAOYSA-N
SMILES: O=C(N1CCS(CC1)(=O)=O)C2=CC=C(OCC3=C(C)ON=C3C4=CC=C(F)C=C4)N=C2
Biological Activity: Basmisanil (RG1662) is a highly selective orally active α subunit-containing GABAA receptors (GABAAα5) negative allosteric modulator (NAMs). Basmisanil can inhibit GABAA-α5 with a Ki value of 5 nM and IC50 value of 8 nM, respectively. Basmisanil can be used for the research of multiple cognitive and psychiatric disorders[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Basmisanil | 99.40% | Basmisanil (RG1662) is a highly selective orally active α subunit-containing GABAA receptors (GABAAα5) negative allosteric modulator (NAMs). Basmisanil can inhibit GABAA-α5 with a Ki value of 5 nM and IC50 value of 8 nM, respectively. Basmisanil can be used for the research of multiple cognitive and psychiatric disorders. | ||||||||||||||||||||
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Keywords
