116754-87-1
Chemical Structure
Iodofiltic acid
- CAS. Nr.: 116754-87-1
- Formula:C22H35IO2
- Molecular Weight:458.42
IUPAC Name: 15-(4-iodophenyl)-3-methylpentadecanoic acid
InChIKey: NPCIWINHUDIWAV-UHFFFAOYSA-N
SMILES: O=C(O)CC(C)CCCCCCCCCCCCC1=CC=C(I)C=C1
Biological Activity: Iodofiltic acid is a terminal p-iodophenyl-substituted β-methyl-branched long-chain fatty acid and myocardial fatty acid metabolism inhibitor. Iodofiltic acid inhibits myocardial fatty acid metabolism via steric or chemical interference due to 3-position methyl branching. Iodofiltic acid shows significant myocardial uptake and prolonged retention in rats, with low in vivo deiodination and high blood levels[1].
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Iodofiltic acid | Iodofiltic acid is a terminal p-iodophenyl-substituted β-methyl-branched long-chain fatty acid and myocardial fatty acid metabolism inhibitor. Iodofiltic acid inhibits myocardial fatty acid metabolism via steric or chemical interference due to 3-position methyl branching. Iodofiltic acid shows significant myocardial uptake and prolonged retention in rats, with low in vivo deiodination and high blood levels. | |||||||||||||||||||||
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