1228357-04-7
Chemical Structure
CDE-096
- CAS No.: 1228357-04-7
- Formula:C25H20F3NO12
- Molecular Weight:583.42
IUPAC Name: 3-(((3-(trifluoromethyl)phenoxy)carbonyl)amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate)
InChIKey: OXWKLJPAKUDPJY-UHFFFAOYSA-N
SMILES: O=C(OC1=CC=CC(C(F)(F)F)=C1)NCC(COC(C2=CC(O)=C(C(O)=C2)O)=O)OC(C3=CC(O)=C(C(O)=C3)O)=O
Biological Activity: CDE-096 is a potent inhibitor of PAI-1. CDE-096 prevents PAI-1 from inactivating tPA and uPA with similar potency (IC50=30 and 25 nM, respectively) and is active against glycosylated PAI-1, as well as PAI-1 derived from several species (IC50=19, 22 and 18 nM for murine, rat, and Porcine PAI-1, respectively)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
CDE-096 | 99.98% | CDE-096 is a potent inhibitor of PAI-1. CDE-096 prevents PAI-1 from inactivating tPA and uPA with similar potency (IC50=30 and 25 nM, respectively) and is active against glycosylated PAI-1, as well as PAI-1 derived from several species (IC50=19, 22 and 18 nM for murine, rat, and Porcine PAI-1, respectively). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.60
HY-N172153,4,6-Tri-O-galloyl-D-glucose -
Similarity Score 0.58
HY-N173513,6-Di-O-galloyl-D-glucopyranoside -
Similarity Score 0.58
HY-N171111,7-Di-O-Galloyl-D-sedoheptulose -
Similarity Score 0.57
HY-N4117Hamamelitannin -
Similarity Score 0.56
HY-110354RUCM05 (Standard) -
Similarity Score 0.56
HY-N174494’,6’-Di-O-galloylsalicin -
Similarity Score 0.56
HY-N17603Ginnalin A -
Similarity Score 0.54
HY-N112851,2,6-Tri-O-galloyl-β-D-glucose -
Similarity Score 0.54
HY-N60061,3,6-Tri-O-galloyl-beta-D-glucose -
Explore the MedChemAI to find more analogs
