1233332-14-3
Chemical Structure
NIBR0213
- CAS No.: 1233332-14-3
- Formula:C27H29ClN2O3
- Molecular Weight:464.98
IUPAC Name: (3'-(((R)-1-(4-chloro-3-methylphenyl)ethyl)amino)-3,5-dimethyl-[1,1'-biphenyl]-4-carbonyl)-L-alanine
InChIKey: KYHUARFFBDLROH-MOPGFXCFSA-N
SMILES: ClC1=CC=C([C@@H](C)NC2=CC=CC(C3=CC(C)=C(C(N[C@@H](C)C(O)=O)=O)C(C)=C3)=C2)C=C1C
Biological Activity: NIBR-0213 is a potent, orally active and selective S1P1 antagonist with efficacy in experimental autoimmune encephalomyelitis. NIBR-0213 displays potent and comparable potency on human and rat S1P1 (IC50 of 2.0 nM and 2.3 nM, respectively) in GTPγ35S assays[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
NIBR0213 | 98.91% | NIBR-0213 is a potent, orally active and selective S1P1 antagonist with efficacy in experimental autoimmune encephalomyelitis. NIBR-0213 displays potent and comparable potency on human and rat S1P1 (IC50 of 2.0 nM and 2.3 nM, respectively) in GTPγ35S assays. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
