1257044-75-9
Chemical Structure
A-1211212
Synonym(s): BCL2-IN-1
- CAS No.: 1257044-75-9
- Formula:C47H54ClN7O7S
- Molecular Weight:896.49
IUPAC Name: 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((((1r,4r)-4-methoxycyclohexyl)methyl)amino)-3-nitrophenyl)sulfonyl)benzamide
InChIKey: CSBKUBOVPUXFLO-MAVVKCOWSA-N
SMILES: O=C(NS(=O)(C1=CC=C(NC[C@H]2CC[C@H](OC)CC2)C([N+]([O-])=O)=C1)=O)C3=CC=C(N4CCN(CC5=C(C6=CC=C(Cl)C=C6)CC(C)(C)CC5)CC4)C=C3OC7=CN=C(NC=C8)C8=C7
Biological Activity: A-1211212 (BCL2-IN-1), a chemical probe, is a potent Bcl-2 inhibitor. BCL2-IN-1 binds Bcl-2 with a Ki of <0.01 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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A-1211212 | 98.43% | A-1211212 (BCL2-IN-1), a chemical probe, is a potent Bcl-2 inhibitor. BCL2-IN-1 binds Bcl-2 with a Ki of <0.01 nM. | ||||||||||||||||||||
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Keywords
